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OZONE IN NON-RHEUMATIC LOCOMOTOR SYSTEM PATHOLOGIES

Alexandre, J. Baeza Noci, V. Sheel Kumar

Биорадикалы и Антиоксиданты. Том 2, №1, Стр. 6-20

Ключевые слова: озон, озонотерапия, заболевания позвоночника, тендопатии, остеоартрит, туннельные синдромы

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Статья опубликована с разрешения Международного научного комитета по проблемам озонотерапии (The Scientific International Committee of Ozone Therapy – ISCO3, www.aepromo.org/en/isco3.php.)

В обзоре, включающем анализ достижений озонотерапии за последние два десятилетия, рассмотрено современнее состояние и применимость метода в ревматологии, неврологии, нейрохирургии и ортопедии. Рассмотрены возможности использования медицинского озона при тендопатиях, остеоартритах и т. д. Отдельное внимание уделено озонотерапии неврологической патологии (в частности, туннельным синдромам), заболеваний позвоночника. Обсуждаются способы введения озона и оптимальные его дозы. Кратко рассмотрены противопоказания к озонотерапии для контингента пациентов с неревматичекой патологией опорно-двигательного аппарата.

Ключевые слова: озон, озонотерапия, заболевания позвоночника, тендопатии, остеоартрит, туннельные синдромы

  1. Verga C. Nuovo approccio terapeutico alle ernie e protusioni discali lombari // Rivista Di Neuroradiologia. 1989. Vol. 2. P. 148.
  2. Riva Sanseverino E. Knee joint disorders treated by oxigen-ozone therapy // Europa Medicophysica. 1989. Vol. 25. N3. P. 163-170.
  3. Escarpenter J., Valdes O. Resultados terapéuticos en la osteoartritis de la rodilla con infiltraciones de ozono // Revista Cubana de Investigación Biomédica. 1997. Vol. 16. P. 124–132.
  4. Gheza G., Ipprio L., Bissolotti L. Oxygen-Ozone Therapy in a Diabetic Patient with De Quervain’s Tenosynovitis Associated with Joint Arthrosis // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 2. N1. P. 189-192.
  5. Gaffuri M, Garaffo R, Gheza G. Oxygen-Ozone Therapy for Lateral Humeral Epicondylitis: Preliminary Findings // Riv. Ital. Ossigeno-Ozonoterapia. 2003. Vol. 2. N2. P. 169-172.
  6. Gheza G., Bissolotti L. Intra-articular Oxygen-Ozone Injection for Knee Биорадикалы и Антиоксиданты 2015 Том 2, No1 15 Disease Proposed Guidelines // Riv. Ital. Ossigeno-Ozonoterapia. 2003. Vol. 2. N1. P. 63–66.
  7. Moretti B., Lanzisera R., Morese A. et al. O2-O3 vs Chondroprotectors in the Treatment of Osteoarthritis of the Knee // Riv Ital Ossigeno-Ozonoterapia. 2004 Vol. 3. N1. P. 65–72.
  8. Pribluda S. Treatment of Lumbosciatica and Other Similar Syndromes with Subcutaneous Ozone // Sem. Med. 1963. Vol. 123. P. 1026–1028.
  9. Magalhaes E., Dotta L., Sasse A. Ozone therapy as a treatment for low back pain secondary to herniated disc: a systematic review and meta-analysis of randomized controlled trials // Pain Physician. Vol. 15, N2. P. E115–129.
  10. Ceccherelli F., Gagliardi G., Faggian L. et al. Analgesic effect of subcutaneous administration of oxygen-ozone. A blind study in the rat on the modulation of the capsaicin-induced edema // Acupunct. Electrother. Res. 1998. Vol. 23. N3-4. P. 171-184.
  11. Iliakis E.M., Valadakis V., Vynios D. et al. Rationalization of the activity of medical ozone on intervertebral disc: a histological and biochemical study // Rivista di Neuroradiologia. 2001, N14. Suppl. 1. P. 23-30.
  12. Iliakis E., Petropoulos I., Iliaki A. et al. Is Medical Ozone Safe when Injected Intra-articularly? // International Journal of Ozone Therapy. 2008. N7.
  13. Bin Yu. Ozone treatment in osteoarthritis; basic and clinical investigation // Proc. of the IV Meeting of the CFOT (Internet). Shenyang; 2012. http://www.cfot.org.cn/news_view.asp?id=364
  14. Kim Y., Jeon B., Kwon K. Ozone Chemonucleolysis on the Lumbar Intervertebral Disc of the Rabbit // J. Korean Neurosurg. Soc. 2003. Vol. 34. N6. P. 570-574.
  15. Li S., Yu G., Chen G. Impact of different concentrations of ozone injection on pathological changes of rabbit skeletal muscle // J. Modern Clin. Med. Bioeng. (Internet). 2006. N6. http://en.cnki.com.cn/Article_en/CJFDTOTAL-
    XDLC200606012.htm
  16. Castrini A., Prignacca E. Treatment Protocol for Herniated Disc with Oxygen-Ozone Therapy in Dog // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 1, N1. P. 113-115.
  17. Yu Z., He X., Chen Y. Influence of ozone on the ultrastructures of nucleus pulposus // J. Intervent. Radiol. (Internet). 2001. N3. http://en.cnki.com.cn/Article_en/CJFDTOTAL-JRFS200103017.htm
  18. Yu Z., He X., Chen Y. et al. // Chin. J. Radiol. [Internet]. 2002. Vol. 50. N4. http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGS200204023.htm
  19. Algara C., Garcia O. Oxygen-ozone percutaneous nucleolysis: an animal model study // Proc. of the 1st world congress on minimally spine surgery. Honolulu; 2008.
  20. Muto M. Intradiscal and Intramuscolar Injection of Oxygen-Ozone: Pathological Evaluation. Work in Progress // Riv. Ital. Ossigeno-Ozonoterapia. 2004. Vol. 3. N1. P. 7-13.
  21. Tian J., Zhang J-Sh., Xiao Y. et al. Oxidative effect of different concentration of ozone injected into porcine normal lumbar disks // Chin. J. Intervent. Биорадикалы и Антиоксиданты 2015 Том 2, No1 16 Imaging Ther. (Internet). 2007. N4. http://en.cnki.com.cn/Article_en/CJFDTOTAL-
    JRYX200704018.htm
  22. Alexandre A., Buric J., Paradiso R. et al. Intradiscal injection of O2-O3 to treat lumbar disc herniations // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 1. N2. P. 165-169.
  23. Andreula C., Muto M., Leonardi M. Interventional spinal procedures // Eur. J. Radiol. 2004. Vol. 50. N2. P. 112-119.
  24. Alexandre A., Corò L., Azuelos A. et al. Intradiscal injection of oxygen-ozone gas mixture for the treatment of cervical disc herniations // Acta Neurochir. 2005. Vol. 92. Suppl. P. 79-82.
  25. Tian J.L., Zhang J.S., Xiao Y.Y. et al. Changes of CSF and spinal pathomorphology after high-concentration ozone injection into the subarachnoid space: an experimental study in pigs // AJNR Am. J. Neuroradiol. 2007. Vol. 28. N6. P. 1051-1054.
  26. Yu B., Lin Q.-R., Wang B.-W. et al. Effect of Intra-Articular Ozone Injection on Degenerative Knee Cartilage in Rats // Int. J. Ozone Ther. 2010. Vol. 9. N1. P. 14–20.
  27. Paoloni M., Di Sante L., Cacchio A. et al. Intramuscular oxygen-ozone therapy in the treatment of acute back pain with lumbar disc herniation: a multicenter,randomized, double-blind, clinical trial of active and simulated lumbar paravertebral injection // Spine. 2009.Vol. 34, N13. P. 1337-1344.
  28. Steppan J., Meaders T., Muto M., Murphy K. A metaanalysis of the effectiveness and safety of ozone treatments for herniated lumbar discs // J. Vasc. Interv. Radiol. 2010. Vol. 21. N4. P. 534-548.
  29. Bocci V. General mechanisms of action of ozonetherapy and pain related mechanism // Rev. Esp. Soc. Dolor. 2005. Vol. 12. N II. P. 24-36.
  30. Bocci V. Ozone: A new medical drug (Internet). Netherlands: Springer, 2005. 295 p.
  31. López-Laserna Ruiz J. Results of Conservative Treatment of Tarsal Tunnel Syndrome: Medical Ozone Infiltration and Surgery // Revista Española de Ozonoterapia. 2012. P. 62.
  32. García-González B., García-Muñoz W., Játiva-Silvestre F. Infiltraciones locales en Cirugía Ortopëdica y Traumatología. Manual de Cirugía Ortopédica y Traumatología - SECOT. 2a ed. Madrid: Editorial Médica Panamericana; 2010. P. 334-342.
  33. Gjonovich A., Girotto L., Sattin G. et al. Oxygen-Ozone Therapy in Shoulder Pain: Clinical Experience // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 1. N1. P. 37-40.
  34. Moretti B., Lanzisera R., Sisti G.L. et al. O2-O3 therapy in tendinopathies and entrapment syndromes // Riv. Ital. Ossigeno-Ozonoterapia. 2005. Vol. 4. N1. P. 20-29.
  35. De Lucas J. Ozone peripherical infiltration. Indications, techniques and clinical experience // Rev. Esp. Soc. Dolor. 2005. Vol. Vol. 12. N II. P. 37-47.
  36. Moretti M. Can Oxygen–Ozone Injections in Sport Overuse Tendinopathies Be a Valid Alternative to Cortisone Therapy? // Int J Ozone Ther. 2010. Vol. 9. N1. P. 21-24.
  37. Moretti M. Effectiveness of Oxygen-Ozone and Hyaluronic Acid Injections in De Quervain’s Syndrome // Int. J. Ozone Ther. 2012. Vol. 11. N1. P. 31-33.
  38. Trenti G., Gheza G. Efficacy of Oxygen-Ozone Pain Therapy Associated with Shock Waves to Treat Calcifying Tendinitis of the Shoulder // Riv. Ital. Ossigeno-
    Ozonoterapia. 2002. Vol. 1. N1. P. 45-50.
  39. Benvenuti P. Oxygen-Ozone Treatment of the Knee, Shoulder and Hip // Riv. Ital. Ossigeno-Ozonoterapia. 2006. Vol. 5. N2. P. 135-144.
  40. Ikonomidis S., Caralambus D., Vakirtzian L., Iliakis E. Nonoperative Treatment of Shoulder Impingement Syndrome with Topical Injections of Medical Oxygen-Ozone Mixture. A double blind clinical trial // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 1, N1. P. 41-44.
  41. Bonetti M. Oxygen-ozone therapy vs epidural steroids injections - CT evaluation // Rivista Di Neuroradiologia. 2000. Vol. 13. N2. P. 203-206.
  42. Baeza-Noci J. Ozonoterapia intrarticular en la gonartrosis // II Curso Teorico ACEOOT. Jeréz de la Frontera; 2006.
  43. Huanqi C., Cruz M. Eficacia y seguridad del ozono intraarticular en artrosis de rodilla refractaria al tratamiento // Rev. Per. Reum. 2006. Vol. 12. N1. P. 21-26.
  44. Baeza-Noci J. Guideline for ozone therapy in degenerative joint diseases // II Meeting of the CFOT. Urumqi; 2008.
  45. Rogelio Milanes J., Acosta Rivera W., Trinchet Ayala E., Hernández Rosales F. The ozonotherapy/Results of the treatment in patients with symptomatic degenerative arthrosis of the knee // Dolor, Clinica y Terapia. 2009. Vol. 6. N4. P. 18-24.
  46. Baeza-Noci J. Osteoartrosis de rodilla. Resultados de la ozonoterapia // II Congreso Nacional SEOT. Marbella; 2009.
  47. Guo D, Zhang X. Study on treatment for knee osteoarthritis by medical ozone // Gansu Med. J. 2010. N1. P. 10-11.
  48. Moretti M. Effectiveness of Treatment with Oxygen-Ozone and Hyaluronic Acid in Osteoarthritis of the Knee // Int. J. Ozone Ther. 2010. Vol. 9. N1. P. 25-29.
  49. Wang J., Zhang Y., Ma Y. Therapeutic Effect of Low Concentration Medical Ozone on Knee Osteoarthritis // J. Liaoning Coll. Tradit. Chin Med. 2010. Vol. 12. N4. P. 17-19.
  50. Baeza-Noci J. Knee osteoarthritis: ozone therapy results // IV International Ozone Congress. Dehli, 2010.
  51. Mishra S.K., Pramanik R., Das P. et al. Role of intra-articulra ozone in osteo-arthritis of knee for functional and symptomatic improvement // Ind. J. Phys. Med. Rehabilit. 2011. Vol. 22. N2. P. 65-69.
  52. Aymale CA. Ozonoterapia en patología artrósica quirúrgica de rodilla Ozone therapy in surgical pathology of arthritic knee // Rio de Janeiro (Brazil). 2011.
  53. Baeza-Noci J. Ozonoterapia en la gonartrosis y la coxartrosis Ozonetherapy in osteoarthritis // Rio de Janeiro (Brazil), 2011.
  54. Baeza-Noci J. Ozonoterapia en la gonartrosis y la coxartrosis // XXXIV Congreso de la SIBB. Córdoba, 2011.
  55. Baeza-Noci J. Ozonoterapia en la patología de cadera del adulto // IX Congreso de la ACEOOT. Granada, 2011.
  56. Baeza-Noci J. Ozone therapy in adult hip pathology // III Meeting of the WFOOT. Brescia, Italy; 2011.
  57. Cabot Dalmau J. Combined Technique of Ozontherapy and Platelet Derived Growth Factors in the Knee Osteoarthritis (Técnica Combinada de Ozonoterapia y Factores de Crecimiento en la Artrosis de Rodilla) // Revista Española de Ozonoterapia; 2011. P. 34-35.
  58. Baeza-Noci J. Ozone and rich-platelet plasma: a good team for knee osteoarthritis. IV Meeting of the CFOT. Shenyang; 2012.
  59. Zambello A., Fumagalli L., Fara B., Bianchi M. Oxygen-Ozone Treatment of Carpal Tunnel Syndrome. Retrospective Study and Literature Review of Conservative and Surgical Techniques // International Journal of Ozone Therapy. 2008. Vol. 7. N1. P. 45-48.
  60. Bocci V. Is it true that ozone is always toxic? The end of a dogma // Toxicol. Appl Pharmacol. 2006. Vol. 216. N3. P. 493–504.
  61. Baeza-Noci J. Ozone spinal infiltration. Physiopathology and mechanism of action Rev Esp Soc Dolor. 2005. Vol. 12[II]. P. 18-23.
  62. Scuccimarra A. The ―Laminoforaminal Technique‖ in Oxygen-Ozone Therapy for Lumbar Disc Herniation // Riv. Ital. Ossigeno-Ozonoterapia. 2003. Vol. 2. N2. P. 193-196.
  63. Zambello A., Fara B., Bianchi M., Tabaracci G. Paravertebral Oxygen-
    Ozone Infiltrations: High versus Low Doses: towards the Minimum Effective Dose // Int. J. Ozone Ther. 2007. Vol. 6. N1. P. 37-41.
  64. Verga C. Il perché ed il come dell’ossigeno ozono nel trattamento della patologia ortopedica // Ossigeno Ozono Terapia: Pratica medica tra certezze e prospettive terapeutiche. Sorrento; 2004.
  65. Muto M., Andreula C., Leonardi M. Treatment of herniated lumbar disc by intradiscal and intraforaminal oxygen-ozone [O2-O3] injection // J. Neuroradiol. 2004. Vol. 31. N3. P. 183-189.
  66. Juncopilla N., Franzini M. The therapy involving the infiltration of oxygen-
    ozone intradisc and interfacet // 1er Congresso de la Sociedad Española de abordajes percutaneos vertebrales. Barcelona; 1995.
  67. Dall’aglio R., Gomez Moraleda M., Cardoso C. et al. Biochemical and Pharmaceutical Aspects of Entrapment: the Possible Role of Free Radicals and Ozone in Nerve Root Compression// Riv. Ital. Ossigeno-Ozonoterapia. 2004. Vol. 3, N2. P. 105-111.
  68. Murga M. Ozone spinal infiltration. Indications, techniques and clinical experience // Rev. Esp. Soc. Dolor. 2005. Vol. 12. N II. P. 10-17.
  69. Leonardi M. Disc Puncture under Fluoroscopic Guidance // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 1. N 1. P. 73-78.
  70. Andreula C.F., Simonetti L., De Santis F. et al. Minimally invasive oxygen-
    ozone therapy for lumbar disk herniation // AJNR Am. J. Neuroradiol. 2003. Vol. 24. N5. P. 996–1000.
  71. He X., Yu Z., Teng G. et al. Treatment of lumbar disc herniation by using percutaneous intradiscal and paraspinal space injection of O_2-O_3 mixture // Chin. J. Radiol. (Internet). 2003. N9. Retrieved from: http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZHGS200309018.htm
  72. Buric J., Molino Lova R. Ozone chemonucleolysis in non-contained lumbar disc herniations: a pilot study with 12 months follow-up // Acta Neurochir. Suppl. 2005. Vol. 92. P. 93-97.
  73. He X.F., Yu Z.J., Li Y.H. et al. Percutaneous injection of intradiscal and paraspinal space with O2-O3 mixture to treat lumbar disc herniation // Riv. Ital. Ossigeno-Ozonoterapia. 2003. Vol. 2. N2. P. 135-138.
  74. He X., Li Y., Chen H. et al. Intradiscal injection of O_2-O_3 to treat lumbar disc herniations: clinical therapeutic effect analysis with 600 cases // Chin. J. Intervent. Imaging Ther. (Internet). 2005. Vol. 2. N5. http://en.cnki.com.cn/Article_en/CJFDTotal-
    JRYX200505004.htm
  75. Buric J., Alexandre A., Corò L., Azuelos A. Intradiscal Ozone Treatment of Non-Contained Disc Herniations. 18 Months Follow-up // Riv. Ital. Ossigeno-
    Ozonoterapia. 2003. Vol. 2. N2. P. 153-160.
  76. Wang J., Li H., Wang G. Studies on the concentration of oxygen-ozone in percutaneous intradiscal oxygen-ozone-injection for the treatment of lumber disc herniation // Chin. J. Spine Spinal Cord (Internet). 2007. N11. http://en.cnki.com.cn/Article_en/CJFDTOTAL-ZJZS200711010.htm
  77. Paradiso R., Alexandre A. The different outcomes of patients with disc herniation treated either by microdiscectomy, or by intradiscal ozone injection // Acta Neurochir Suppl. 2005. Vol. 92. P. 139-142.
  78. Bonetti M. CT-Guided Intraforaminal Technique // Riv. Ital. Ossigeno-
    Ozonoterapia. 2002. Vol. 1. N1. P. 69-71.
  79. Andreula C. Lumbosacral Herniated Discs: Chemodiscolysis with Nucleophthesis with O2-O3 and Periradicular and Periganglionic Infiltration under CT Guidance Personal Experience // Riv. Ital. Ossigeno-Ozonoterapia. 2002. Vol. 1. N1. P. 79-85.
  80. Andreula C. Ozone therapy // Neuroradiology. 2011. Vol. 53. Suppl. 1. P. S207-209.
  81. Mattozi I., Laurini G., Muzzi G. et al. Intrasacral epidural injection with oxygen-ozone for the treatment of low back pain. Comparison and evaluation with other techniques and rehabilitation and return to work // European Journal of Clinical Investigation. 2003. Vol. 33 [suppl. 1]. P. 45.
  82. Morales E. Peridural ozone therapy in disc-radicular conflcit and lumbosciatalgia // Jornadas Científicas SEOT 2012. Valencia; 2012.
  83. Baeza-Noci J. Spinal ozone therapy - state of the art // Congreso Nazionale FIO. Bologna; 2007.
  84. Baeza-Noci J. Rational use of ozone therapy in degenerative spinal pathologies// 6th European Course ―Minimally invasive surgery of the spine.‖ Treviso; 2008.
  85. Baeza-Noci J., Kumar V. Ozone discectomy (ozonucleolysis) for discogenic radiculopathy arising from disc herniation: one year follow-up study from Indian and Spanish centres. Spineweek. Geneve; 2008.
  86. Baeza-Noci J. Ozone Therapy in the Musculo-Skeletal Pathology: Spine // III Meeting of the WFOOT. Brescia, Italy; 2011.
  87. Bonetti M. CT-Guided Oxygen-Ozone Infiltration into Isthmic Lysis Points in the Management of 1st Degree Spondylolisthesis and Spondylolysis // Riv. Ital.Ossigeno-Ozonoterapia. 2003. Vol. 2. N1. P. 31-38.
  88. Bonetti M., Fontana A., Albertini F. CT-guided oxygen-ozone treatment for first degree spondylolisthesis and spondylolysis // Acta Neurochir. Suppl. 2005. Vol. 92. P. 87-92.
  89. Bonetti M., Cotticelli B., Richelmi P., Valdenassi L. Rofecoxib and O2-O3 Therapy vs O2-O3 Therapy in the Management of Spondylarthrosis // Riv. Ital.Ossigeno-Ozonoterapia. 2002. Vol. 1. N2. P. 171-178.
  90. Bonetti M., Fontana A., Mardighian D. Oxygen-ozone therapy for degenerative spine disease in the elderly // Riv. Ital. Ossigeno-Ozonoterapia. 2006. Vol. 5. N1. P. 25-32.
  91. Bonetti M., Fontana A., Parodi F. Oxygen-Ozone Therapy Associated with Magnetic Bioresonance in Degenerative Arthrosis of the Spine: Preliminary Findings // Int. J. Ozone Ther. 2007. Vol. 6. N1. P. 29-35.
  92. Bonetti M., Fontana A., Martinelli F., Andreula C. Oxygen-ozone therapy for degenerative spine disease in the elderly: a prospective study // Acta Neurochir. Suppl. 2011. Vol. 108. P. 137-142.
  93. Baeza-Noci J. Spinal Ozone Therapy in Lumbar Spinal Stenosis // Int. J. Ozone Ther. 2007. Vol. 6. N1. P. 17-24.

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